Interactive Clinical Workbench
MedOrqis v2.1.1 Kernel
Clinical Playground
Test real clinical scenarios, run deterministic mathematical engines, and inspect step-by-step mathematical derivations without token hallucination.
Select Patient Scenario:
Cardiology & Nephrology
Elderly Diabetic Patient with Atrial Fibrillation & CKD
3 Calculators
Pediatrics & Infectious Diseases
Pediatric Acute Otitis Media Weight-Dose Capping
2 Calculators
Orthopedics & Vascular Surgery
Postoperative Knee Arthroplasty with Unilateral Calf Swelling
2 Calculators
Emergency Medicine & Pulmonology
Emergency Room Community-Acquired Pneumonia Assessment
2 Calculators
Cardiology & Health Policy
Cardiology Guidelines Divergence: ESC 2024 vs ACC/AHA 2023
2 Calculators
Cardiology & Nephrology
Elderly Diabetic Patient with Atrial Fibrillation & CKD
72-year-old male presenting with palpitation and fatigue. Medical history includes hypertension, type 2 diabetes mellitus, and a remote TIA 3 years ago. Baseline serum creatinine is 1.4 mg/dL, weight 78 kg, height 175 cm.
Recommended:
Active Calculator
2024
CHA2DS2-VA (ESC 2024 Guidelines)
HIGH RISK
2024 ESC Guidelines for the management of atrial fibrillation (Van Gelder IC et al. Eur Heart J 2024) (2024)
CHA2DS2-VA (ESC 2024 Guidelines)
Applicable Population: Adults (>= 18 years) with non-valvular atrial fibrillation
Calculated Score:
5
points
Clinical Interpretation
High Thromboembolic Risk (5 points)
Guideline-Directed Recommendation
Oral anticoagulation IS RECOMMENDED (Class I), preferably DOAC over VKA unless mechanical valve or moderate-severe mitral stenosis. Assess HAS-BLED bleeding risk.
Clinical Alerts & Safety Warnings
- Always assess renal function (CrCl via Cockcroft-Gault) prior to DOAC dosing.
Deterministic Execution Trace
Zero-Token Arithmetic
Mathematical Formula
\text{Score} = C + H + A_2 + D + S_2 + V \quad (\text{Range: } 0-8)
Step-by-Step Formula Progression:
1
+1: Hypertension history or anti-hypertensive therapy
2
+1: Age 65-74 years
3
+1: Diabetes Mellitus
4
+2: Prior Stroke, TIA, or systemic thromboembolism
5
NOTE: Biological sex category REMOVED in ESC 2024 guideline (score range 0-8).
Invariant Input Payload:
{
"age_years": 72,
"biological_sex": "MALE",
"hx_heart_failure": false,
"hx_hypertension": true,
"hx_diabetes": true,
"hx_stroke_tia_thromboembolism": true,
"hx_vascular_disease": false,
"serum_creatinine_mg_dl": 1.4,
"weight_kg": 78,
"height_cm": 175,
"uncontrolled_hypertension_sbp_gt_160": false,
"abnormal_renal_function": false,
"abnormal_liver_function": false,
"stroke_history": true,
"prior_major_bleeding_or_predisposition": false,
"labile_inr": false,
"medications_antiplatelets_nsaids": false,
"alcohol_excess": false
}